Conducting Polymers in Neural Stimulation Applications
Identifieur interne : 003978 ( Main/Exploration ); précédent : 003977; suivant : 003979Conducting Polymers in Neural Stimulation Applications
Auteurs : David D. Zhou [États-Unis] ; X. Tracy Cui [États-Unis] ; Amy Hines [États-Unis] ; Robert J. Greenberg [États-Unis]Source :
- Biological and Medical Physics, Biomedical Engineering [ 1618-7210 ]
Abstract
Abstract: With advances in neural prostheses, the demand for high-resolution and site-specific stimulation is driving microelectrode research to develop electrodes that are much smaller in area and longer in lifetime. For such arrays, the choice of electrode material has become increasingly important. Currently, most neural stimulation devices use platinum, iridium oxide, or titanium nitride electrodes. Although those metal electrodes have low electrode impedance, high charge injection capability, and high corrosion resistance, the neural interface between solid metal and soft tissue has undesilable characteristics. Recently, several conducting polymers, also known as inherently conducting polymers (ICPs), have been explored as new electrode materials for neural interfaces. Polypyrrole (PPy), polyaniline (PANi), and poly(3,4-ethylenedioxythiophene) (PEDOT) polymers may offer the organic, improved bionic interface that is necessary to promote biocompatibility in neural stimulation applications. While conducting polymers hold much promise in biomedical applications, more research is needed to further understand the properties of these materials. Factors such as electrode impedance, polymer volume changes under electrical stimulation, charge injection capability, biocompatibility, and long-term stability are of significant importance and may pose as challenges in the future success of conducting polymers in biomedical applications. This chapter looks into the current research and challenges for conducting polymers and their applications in neural stimulation electrodes.
Url:
DOI: 10.1007/978-0-387-98120-8_8
Affiliations:
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Zhou</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Second Sight Medical Products, Inc., Sylmar Biomedical Park, 91342, Sylmar, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation></affiliation></author><author><name sortKey="Cui, X Tracy" sort="Cui, X Tracy" uniqKey="Cui X" first="X. Tracy" last="Cui">X. Tracy Cui</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Bioengineering, University of Pittsburgh, 15261, Pittsburgh, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation><affiliation wicri:level="1"><country wicri:rule="url">États-Unis</country></affiliation></author><author><name sortKey="Hines, Amy" sort="Hines, Amy" uniqKey="Hines A" first="Amy" last="Hines">Amy Hines</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Second Sight Medical Products, Inc., Sylmar Biomedical Park, 91342, Sylmar, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation></affiliation></author><author><name sortKey="Greenberg, Robert J" sort="Greenberg, Robert J" uniqKey="Greenberg R" first="Robert J." last="Greenberg">Robert J. Greenberg</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Second Sight Medical Products, Inc., Sylmar Biomedical Park, 91342, Sylmar, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="s" type="main" xml:lang="en">Biological and Medical Physics, Biomedical Engineering</title><title level="s" type="abbrev">Biological and Medical Physics, Biomedical Engineering</title><idno type="ISSN">1618-7210</idno><idno type="ISSN">1618-7210</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1618-7210</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: With advances in neural prostheses, the demand for high-resolution and site-specific stimulation is driving microelectrode research to develop electrodes that are much smaller in area and longer in lifetime. For such arrays, the choice of electrode material has become increasingly important. Currently, most neural stimulation devices use platinum, iridium oxide, or titanium nitride electrodes. Although those metal electrodes have low electrode impedance, high charge injection capability, and high corrosion resistance, the neural interface between solid metal and soft tissue has undesilable characteristics. Recently, several conducting polymers, also known as inherently conducting polymers (ICPs), have been explored as new electrode materials for neural interfaces. Polypyrrole (PPy), polyaniline (PANi), and poly(3,4-ethylenedioxythiophene) (PEDOT) polymers may offer the organic, improved bionic interface that is necessary to promote biocompatibility in neural stimulation applications. While conducting polymers hold much promise in biomedical applications, more research is needed to further understand the properties of these materials. Factors such as electrode impedance, polymer volume changes under electrical stimulation, charge injection capability, biocompatibility, and long-term stability are of significant importance and may pose as challenges in the future success of conducting polymers in biomedical applications. This chapter looks into the current research and challenges for conducting polymers and their applications in neural stimulation electrodes.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li><li>Pennsylvanie</li></region><settlement><li>Pittsburgh</li></settlement><orgName><li>Université de Pittsburgh</li></orgName></list><tree><country name="États-Unis"><region name="Californie"><name sortKey="Zhou, David D" sort="Zhou, David D" uniqKey="Zhou D" first="David D." last="Zhou">David D. Zhou</name></region><name sortKey="Cui, X Tracy" sort="Cui, X Tracy" uniqKey="Cui X" first="X. Tracy" last="Cui">X. Tracy Cui</name><name sortKey="Cui, X Tracy" sort="Cui, X Tracy" uniqKey="Cui X" first="X. Tracy" last="Cui">X. Tracy Cui</name><name sortKey="Greenberg, Robert J" sort="Greenberg, Robert J" uniqKey="Greenberg R" first="Robert J." last="Greenberg">Robert J. Greenberg</name><name sortKey="Hines, Amy" sort="Hines, Amy" uniqKey="Hines A" first="Amy" last="Hines">Amy Hines</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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